BDBM50230988 CHEMBL4089697

SMILES CC(C)CC1N(C(N)=NC1=O)c1nc(NC2CCC(CC2)Nc2nc(NC(N)=N)nc(n2)N2C(CC(C)C)C(=O)N=C2N)nc(NC(N)=N)n1

InChI Key InChIKey=LJIPKOGDUOMUGC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50230988   

TargetAtrial natriuretic peptide receptor 1(Rat)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50230988(CHEMBL4089697)
Affinity DataEC50:  76nMAssay Description:Agonist activity at rat NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 15 mins by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2019
Entry Details Article
PubMed
TargetAtrial natriuretic peptide receptor 1(Human)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50230988(CHEMBL4089697)
Affinity DataEC50:  8.10nMAssay Description:Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2019
Entry Details Article
PubMed