BDBM50230529 (S)-N,2-dihydroxy-3-(N-(4-(4-(trifluoromethyl)phenoxy)phenyl)methan-15-ylsulfonamido)propanamide::(S)-N,2-dihydroxy-3-(N-(4-(4-(trifluoromethyl)phenoxy)phenyl)methan-8-ylsulfonamido)propanamide::CHEMBL252826

SMILES CS(=O)(=O)N(C[C@H](O)C(=O)NO)c1ccc(Oc2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=KCAMDNAUAMLPGX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50230529   

TargetMatrix metalloproteinase-9(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50230529((S)-N,2-dihydroxy-3-(N-(4-(4-(trifluoromethyl)phen...)
Affinity DataIC50: 14nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50230529((S)-N,2-dihydroxy-3-(N-(4-(4-(trifluoromethyl)phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50230529((S)-N,2-dihydroxy-3-(N-(4-(4-(trifluoromethyl)phen...)
Affinity DataIC50: 139nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50230529((S)-N,2-dihydroxy-3-(N-(4-(4-(trifluoromethyl)phen...)
Affinity DataIC50: 139nMAssay Description:Inhibition of full length MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50230529((S)-N,2-dihydroxy-3-(N-(4-(4-(trifluoromethyl)phen...)
Affinity DataIC50: 14nMAssay Description:Inhibition of catalytic domain MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed