BDBM50230347 CHEMBL4096521

SMILES Clc1ccc(cc1)C(=O)C(=S)N1CCOCC1

InChI Key InChIKey=IWEPJEXBCDPDQS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50230347   

TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50: 5.05E+4nMAssay Description:Inhibition of PHGDH in human HL60 cells assessed as reduction in cell viability in serine repleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PHGDH (1 to 533 residues) expressed in Escherichia coli assessed as reduction in NADH formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of PHGDH in human SiHa cells assessed as reduction in cell viability in serine depleted medium after 5 days by presto blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50230347(CHEMBL4096521)
Affinity DataIC50: 8.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed