BDBM50230005 1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea::CHEMBL439259::N-(2-methoxy-5-chlorophenyl)-N-(2-methylquinolin-4-yl)-urea::TCMDC-125497

SMILES COc1ccc(Cl)cc1NC(=O)Nc1cc(C)nc2ccccc12

InChI Key InChIKey=YBLWOZUPHDKFOT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50230005   

TargetInsulin-like growth factor 1 receptor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(TCMDC-125497 | 1-(5-chloro-2-methoxyphenyl)-3-(2-m...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IGF1R autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(TCMDC-125497 | 1-(5-chloro-2-methoxyphenyl)-3-(2-m...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of IGF1R-dependent tumor cell growth in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(TCMDC-125497 | 1-(5-chloro-2-methoxyphenyl)-3-(2-m...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of IGF1R autophosphorylation in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(TCMDC-125497 | 1-(5-chloro-2-methoxyphenyl)-3-(2-m...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of IGF1R autophosphorylation in human MCF7 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(TCMDC-125497 | 1-(5-chloro-2-methoxyphenyl)-3-(2-m...)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of recombinant IGF1R by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(TCMDC-125497 | 1-(5-chloro-2-methoxyphenyl)-3-(2-m...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of IGF1R-dependent tumor cell growth in human MCNeuA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(TCMDC-125497 | 1-(5-chloro-2-methoxyphenyl)-3-(2-m...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IGF1R in growth factor-stimulated NHDFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed