BDBM50229909 CHEMBL83403

SMILES Cc1cc(NCc2ccccc2)c2cc(NC(=O)\C=C\c3ccccc3Cl)ccc2n1

InChI Key InChIKey=IUHCXLNWSPBOKX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50229909   

TargetMyeloperoxidase(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229909(CHEMBL83403)
Affinity DataEC50: 15.00E+3nMAssay Description:Compound was tested for the induction of nonspecific myeloperoxidase (MPO) releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2019
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229909(CHEMBL83403)
Affinity DataIC50: 2.33E+5nMAssay Description:Ability to inhibit binding of radiolabeled C5a anaphylatoxin to intact membrane bound receptor from human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2019
Entry Details Article
PubMed