BDBM50229642 (S)-tetrahydrofuran-3-yl 4-((4-(2-fluorophenyl)piperidin-1-ylsulfonyl)methyl)-4-(hydroxycarbamoyl)piperidine-1-carboxylate::CHEMBL252627

SMILES ONC(=O)C1(CS(=O)(=O)N2CCC(CC2)c2ccccc2F)CCN(CC1)C(=O)O[C@H]1CCOC1

InChI Key InChIKey=JWVKYLLQNXGDRB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50229642   

TargetMatrix metalloproteinase-9(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50229642((S)-tetrahydrofuran-3-yl 4-((4-(2-fluorophenyl)pip...)
Affinity DataIC50: 100nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50229642((S)-tetrahydrofuran-3-yl 4-((4-(2-fluorophenyl)pip...)
Affinity DataIC50: 76nMAssay Description:Inhibition of HER2 sheddase in human BT474 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50229642((S)-tetrahydrofuran-3-yl 4-((4-(2-fluorophenyl)pip...)
Affinity DataIC50: 942nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50229642((S)-tetrahydrofuran-3-yl 4-((4-(2-fluorophenyl)pip...)
Affinity DataIC50: 135nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50229642((S)-tetrahydrofuran-3-yl 4-((4-(2-fluorophenyl)pip...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50229642((S)-tetrahydrofuran-3-yl 4-((4-(2-fluorophenyl)pip...)
Affinity DataIC50: 44nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed