BDBM50229606 CHEMBL4072591

SMILES CCC(C)(C)C(=O)N(O)Cc1ccc(F)c(F)c1

InChI Key InChIKey=BVSNZWPRMVHHAR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229606   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
National Institute of Biological Sciences

Curated by ChEMBL
LigandPNGBDBM50229606(CHEMBL4072591)
Affinity DataEC50:  56nMAssay Description:Inhibition of RIP1 in human HT-29 cells assessed as reduction in TNFalpha/z-VAD-FMK-induced necrosis after 24 hrs by Cell Titer-Glo luminescent cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2019
Entry Details Article
PubMed