BDBM50229200 CHEMBL251817::N-(2-amino-5-(thiophen-2-yl)phenyl)-4-(butyramidomethyl)benzamide::US9096559, 38

SMILES CCCC(=O)NCc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1

InChI Key InChIKey=OPGJYOJXMZIXKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50229200   

TargetHistone deacetylase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50229200(N-(2-amino-5-(thiophen-2-yl)phenyl)-4-(butyramidom...)
Affinity DataIC50: 12nMAssay Description:Novel compounds were tested for their ability to inhibit histone deacetylase, subtype 1 (HDAC1) using an in vitro deacetylation assay. The enzyme sou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50229200(N-(2-amino-5-(thiophen-2-yl)phenyl)-4-(butyramidom...)
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed