BDBM50229199 CHEMBL398884::thiophene-2-carboxylic acid (4-hydroxy-biphenyl-3-yl)-amide

SMILES Oc1ccc(cc1NC(=O)c1cccs1)-c1ccccc1

InChI Key InChIKey=ZDKNSGWZSHUWOU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50229199   

TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229199(thiophene-2-carboxylic acid (4-hydroxy-biphenyl-3-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229199(thiophene-2-carboxylic acid (4-hydroxy-biphenyl-3-...)
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229199(thiophene-2-carboxylic acid (4-hydroxy-biphenyl-3-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229199(thiophene-2-carboxylic acid (4-hydroxy-biphenyl-3-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed