BDBM50229196 CHEMBL253227::N-(4-amino-biphenyl-3-yl)-4-[(cyclohexanecarbonyl-amino)-methyl]-benzamide::US9096559, 14i

SMILES Nc1ccc(cc1NC(=O)c1ccc(CNC(=O)C2CCCCC2)cc1)-c1ccccc1

InChI Key InChIKey=URTRVFWUUAICBJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50229196   

TargetHistone deacetylase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50229196(N-(4-amino-biphenyl-3-yl)-4-[(cyclohexanecarbonyl-...)
Affinity DataIC50: 42nMAssay Description:Novel compounds were tested for their ability to inhibit histone deacetylase, subtype 1 (HDAC1) using an in vitro deacetylation assay. The enzyme sou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50229196(N-(4-amino-biphenyl-3-yl)-4-[(cyclohexanecarbonyl-...)
Affinity DataIC50: 20nMAssay Description:Novel compounds were tested for their ability to inhibit histone deacetylase, subtype 1 (HDAC1) using an in vitro deacetylation assay. The enzyme sou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50229196(N-(4-amino-biphenyl-3-yl)-4-[(cyclohexanecarbonyl-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed