BDBM50228840 (S)-1-[(R)-2-(3,3-dimethyl-butyrylamino)-3-phenyl-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-(benzooxazole-2-carbonyl)-4-guanidino-butyl]-amide; TFA::CHEMBL436851

SMILES [#6]C([#6])([#6])[#6]-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-c1nc2ccccc2o1

InChI Key InChIKey=GTYRDHOPZLWHCA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50228840   

TargetPlasminogen(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50228840((S)-1-[(R)-2-(3,3-dimethyl-butyrylamino)-3-phenyl-...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibitory concentration against plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50228840((S)-1-[(R)-2-(3,3-dimethyl-butyrylamino)-3-phenyl-...)
Affinity DataIC50: 68nMAssay Description:Inhibitory concentration against thrombin(FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerine protease 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50228840((S)-1-[(R)-2-(3,3-dimethyl-butyrylamino)-3-phenyl-...)
Affinity DataIC50: 2.30nMAssay Description:Inhibitory concentration against trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50228840((S)-1-[(R)-2-(3,3-dimethyl-butyrylamino)-3-phenyl-...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50228840((S)-1-[(R)-2-(3,3-dimethyl-butyrylamino)-3-phenyl-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed