BDBM50228418 CHEMBL393591::methyl 1-(diphenoxyphosphoryl)-2-(4-guanidinophenyl)ethylcarbamate

SMILES [#6]-[#8]-[#6](=O)-[#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1

InChI Key InChIKey=RIPAEQJAJRABOY-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50228418   

TargetUrokinase-type plasminogen activator(Mouse)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(methyl 1-(diphenoxyphosphoryl)-2-(4-guanidinopheny...)
Affinity DataIC50: 32nMAssay Description:Inhibition of mouse uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(methyl 1-(diphenoxyphosphoryl)-2-(4-guanidinopheny...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetPlasminogen(Mouse)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(methyl 1-(diphenoxyphosphoryl)-2-(4-guanidinopheny...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of mouse plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetPlasminogen(Rat)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(methyl 1-(diphenoxyphosphoryl)-2-(4-guanidinopheny...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of rat plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProthrombin(Mouse)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(methyl 1-(diphenoxyphosphoryl)-2-(4-guanidinopheny...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of mouse thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(methyl 1-(diphenoxyphosphoryl)-2-(4-guanidinopheny...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human recombinant tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProthrombin(Rat)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(methyl 1-(diphenoxyphosphoryl)-2-(4-guanidinopheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(methyl 1-(diphenoxyphosphoryl)-2-(4-guanidinopheny...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Rat)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(methyl 1-(diphenoxyphosphoryl)-2-(4-guanidinopheny...)
Affinity DataIC50: 19.5nMAssay Description:Inhibition of rat uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50228418(methyl 1-(diphenoxyphosphoryl)-2-(4-guanidinopheny...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed