BDBM50228407 8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methyl-but-2-enyl)-1-(2-oxo-2-phenyl-ethyl)-3,7-dihydro-purine-2,6-dione::CHEMBL237488

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-n1c(nc2n(-[#6])c(=O)n(-[#6]-[#6](=O)-c3ccccc3)c(=O)c12)-[#7]-1-[#6]-[#6]-[#6]-[#6@@H](-[#7])-[#6]-1

InChI Key InChIKey=ZUXRZVPVHVFNSX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50228407   

TargetDipeptidyl peptidase 4(Pig)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50: 40nMAssay Description:Inhibition of porcine DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of porcine DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human DPP4 using H-Gly-Pro-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human DPP4 in Caco-2 cells by fluorescene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50228407(8-((R)-3-amino-piperidin-1-yl)-3-methyl-7-(3-methy...)
Affinity DataIC50: 25nMAssay Description:Displacement of [N-methyl-3H]scopolamine from human recombinant muscarinic M1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed