BDBM50228239 CHEMBL2093965

SMILES COC(O)=C1[C@@H](C(C(=O)OCCN(C)C[C@@H]2COc3ccccc3O2)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=JBGWBMCVMVJNTC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50228239   

LigandPNGBDBM50228239(CHEMBL2093965)
Affinity DataIC50: 1.90E+4nMAssay Description:Alpha-2-adrenolytic activity was assessed from the ability to inhibit [3H]yohimbine binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228239(CHEMBL2093965)
Affinity DataIC50: 2.00E+3nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228239(CHEMBL2093965)
Affinity DataIC50: 1.00E+4nMAssay Description:Alpha-2-adrenolytic activity was assessed in vitro from the ability to inhibit norepinephrine binding to guinea pig vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed