BDBM50228235 CHEMBL554235

SMILES COC(O)=C1C(C(C(=O)OCCN(C)C(C2CCCCC2)c2ccccc2)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=TWNAUTMQNPBBFJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50228235   

LigandPNGBDBM50228235(CHEMBL554235)
Affinity DataIC50: 1.60E+4nMAssay Description:Ability to inhibit [3H]yohimbine binding to alpha-2 adrenergic receptor of rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228235(CHEMBL554235)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro ability to inhibit norepinephrine binding to alpha-2 adrenergic receptor of guinea pig vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228235(CHEMBL554235)
Affinity DataIC50: 1.00E+5nMAssay Description:Alpha-1-adrenolytic activity was assessed in vitro from the ability to inhibit clonidine binding to rat aorta preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Institut De Pharmacologie (Ua 589 Cnrs)

Curated by ChEMBL
LigandPNGBDBM50228235(CHEMBL554235)
Affinity DataIC50: 7.50E+4nMAssay Description:Alpha-1-adrenolytic activity was assessed from the ability to inhibit [3H]prazosin binding to rat cerebral cortex preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2019
Entry Details Article
PubMed