BDBM50228081 (S)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1H-indol-7-yl)methanesulfonamide::CHEMBL391439

SMILES C[C@@](C1CC1)(c1c[nH]c2c(NS(C)(=O)=O)cccc12)c1ccc(F)cc1

InChI Key InChIKey=MIAURGNSNSBTNK-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50228081   

TargetMineralocorticoid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228081((S)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Affinity DataKi:  7.5nMAssay Description:Binding affinity to human mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228081((S)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Affinity DataKi:  313nMAssay Description:Binding affinity to human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228081((S)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Affinity DataKi:  387nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228081((S)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Affinity DataKi:  590nMAssay Description:Binding affinity to human androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228081((S)-N-(3-(1-cyclopropyl-1-(4-fluorophenyl)ethyl)-1...)
Affinity DataKi: >1.10E+3nMAssay Description:Binding affinity to human estrogen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed