BDBM50227751 3-(4-(3-((5,6-dichloro-1H-indole-2-carboxamido)methyl)phenoxy)-2-methylphenyl)propanoic acid::CHEMBL399217

SMILES Cc1cc(Oc2cccc(CNC(=O)c3cc4cc(Cl)c(Cl)cc4[nH]3)c2)ccc1CCC(O)=O

InChI Key InChIKey=DCPNQRIWTPRDLD-UHFFFAOYSA-N

Data  6 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50227751   

LigandPNGBDBM50227751(3-(4-(3-((5,6-dichloro-1H-indole-2-carboxamido)met...)
Affinity DataEC50:  238nMAssay Description:Agonist activity at human PPARgamma expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50227751(3-(4-(3-((5,6-dichloro-1H-indole-2-carboxamido)met...)
Affinity DataIC50: 95nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-{propyl-(5-pyridin-2-yl-thiophene-2-sulfonyl)-amino}-propyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50227751(3-(4-(3-((5,6-dichloro-1H-indole-2-carboxamido)met...)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50227751(3-(4-(3-((5,6-dichloro-1H-indole-2-carboxamido)met...)
Affinity DataIC50: 4.35E+3nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50227751(3-(4-(3-((5,6-dichloro-1H-indole-2-carboxamido)met...)
Affinity DataEC50:  1.89E+3nMAssay Description:Agonist activity at human PPARalpha expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50227751(3-(4-(3-((5,6-dichloro-1H-indole-2-carboxamido)met...)
Affinity DataEC50:  59nMAssay Description:Agonist activity at human PPARdelta expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50227751(3-(4-(3-((5,6-dichloro-1H-indole-2-carboxamido)met...)
Affinity DataIC50: 4.36E+3nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50227751(3-(4-(3-((5,6-dichloro-1H-indole-2-carboxamido)met...)
Affinity DataIC50: 5nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50227751(3-(4-(3-((5,6-dichloro-1H-indole-2-carboxamido)met...)
Affinity DataIC50: 95.1nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed