BDBM50227738 2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)benzamido)methyl)phenoxy)-2-methylphenoxy)-2-methylpropanoic acid::CHEMBL237520

SMILES Cc1cc(Oc2ccc(F)c(CNC(=O)c3ccc(cc3F)C(F)(F)F)c2)ccc1OC(C)(C)C(O)=O

InChI Key InChIKey=HNESZXCOTZCFMK-UHFFFAOYSA-N

Data  9 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50227738   

LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-{propyl-(5-pyridin-2-yl-thiophene-2-sulfonyl)-amino}-propyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataIC50: 384nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataEC50:  119nMAssay Description:Agonist activity at human PPARdelta expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataEC50:  1.05E+3nMAssay Description:Agonist activity at human PPARalpha expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human PPARgamma expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataIC50: 8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataIC50: 384nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataIC50: 3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataIC50: 8nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataIC50: 384nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50227738(2-(4-(4-fluoro-3-((2-fluoro-4-(trifluoromethyl)ben...)
Affinity DataIC50: 3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed