BDBM50227718 (R)-3-((S)-1-((S)-2-methoxy-1-phenylethylamino)-3,3-dimethyl-1-oxobutan-2-ylcarbamoyl)-6-(2-methylbiphenyl-4-yl)hexanoic acid::(R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoyl)-2,2-dimethyl-propylcarbamoyl]-6-(2-methyl-biphenyl-4-yl)-hexanoic acid::CHEMBL250266

SMILES COC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCc1ccc(c(C)c1)-c1ccccc1)CC(O)=O)C(C)(C)C)c1ccccc1

InChI Key InChIKey=NSMABJUGSNPHMN-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50227718   

TargetMatrix metalloproteinase-14(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoy...)
Affinity DataIC50: 6.69E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoy...)
Affinity DataIC50: 3.04E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoy...)
Affinity DataIC50: 6.69E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoy...)
Affinity DataIC50: 3.04E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoy...)
Affinity DataIC50: 23nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoy...)
Affinity DataIC50: 3.42E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoy...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoy...)
Affinity DataIC50: 23nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoy...)
Affinity DataIC50: 3.42E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227718((R)-3-[(S)-1-((S)-2-methoxy-1-phenyl-ethylcarbamoy...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed