BDBM50227709 CHEMBL251917::N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl)-3-methylphenyl)piperidin-1-ylsulfonyl)-2-methylpropanamide

SMILES Cc1cc(ccc1-c1cccc(OCCO)n1)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO

InChI Key InChIKey=YVBOXQAMDNUBQA-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50227709   

TargetMatrix metalloproteinase-9(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50227709(N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50227709(N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50227709(N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50227709(N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 529nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 529nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50227709(N-hydroxy-2-(4-(4-(6-(2-hydroxyethoxy)pyridin-2-yl...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed