BDBM50227603 CHEMBL445939::isopropyl 6-oxo-1,6-dihydropyridine-2-carboxylate

SMILES CC(C)OC(=O)c1cccc(=O)[nH]1

InChI Key InChIKey=NMJHXOZWEMYWQH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50227603   

TargetMatrix metalloproteinase-9(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227603(isopropyl 6-oxo-1,6-dihydropyridine-2-carboxylate ...)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227603(isopropyl 6-oxo-1,6-dihydropyridine-2-carboxylate ...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227603(isopropyl 6-oxo-1,6-dihydropyridine-2-carboxylate ...)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227603(isopropyl 6-oxo-1,6-dihydropyridine-2-carboxylate ...)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed