BDBM50226937 CHEMBL289153

SMILES C(N1C(Cc2ccccc12)C1=NCCN1)c1ccccc1

InChI Key InChIKey=HSCMVYRTOPBJCA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50226937   

LigandPNGBDBM50226937(CHEMBL289153)
Affinity DataKi:  1.90nMAssay Description:Inhibition of saturable binding of [3H]idazoxan to alpha2-site in rat cerebral cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2019
Entry Details Article
PubMed
LigandPNGBDBM50226937(CHEMBL289153)
Affinity DataKi:  2.30nMAssay Description:Binding affinity against alpha-2 adrenergic receptor was determined by the displacement of [3H]clonidine from rat brain cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2018
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Reckitt and Colman

Curated by ChEMBL
LigandPNGBDBM50226937(CHEMBL289153)
Affinity DataKi:  18nMAssay Description:Inhibition of saturable binding of [3H]prazosin to alpha-1 adrenergic receptor in rat cerebral cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2019
Entry Details Article
PubMed