BDBM50226672 CHEMBL255034::makisterone A

SMILES C[C@H](C[C@@H](O)[C@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)[C@H]3CC[C@]12C)C(C)(C)O

InChI Key InChIKey=IJRBORPEVKCEQD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50226672   

TargetCytochrome P450 3A4(Human)
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50226672(makisterone A | CHEMBL255034)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetEcdysone receptor(Fruit fly)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50226672(makisterone A | CHEMBL255034)
Affinity DataIC50: 112nMAssay Description:Binding affinity to ecdysone receptor ligand binding domain in Drosophila melanogaster assessed as number of hydrogen bonds formedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetEcdysone receptor/Ultraspiracle(Southern green stink bug)
Csiro Materials Science and Engineering and Csiro Food and Nutritional Sciences

Curated by ChEMBL
LigandPNGBDBM50226672(makisterone A | CHEMBL255034)
Affinity DataIC50: 1.38E+3nMAssay Description:Binding affinity to Nezara viridula EcRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetUltraspiracle isoform B(Colorado potato beetle)
Csiro Materials Science and Engineering and Csiro Food and Nutritional Sciences

Curated by ChEMBL
LigandPNGBDBM50226672(makisterone A | CHEMBL255034)
Affinity DataIC50: 1.74E+3nMAssay Description:Binding affinity to Leptinotarsa decemlineata EcRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEcdysone receptor/Ultraspiracle protein(Fall armyworm)
Csiro Materials Science and Engineering and Csiro Food and Nutritional Sciences

Curated by ChEMBL
LigandPNGBDBM50226672(makisterone A | CHEMBL255034)
Affinity DataIC50: 389nMAssay Description:Binding affinity to Spodoptera frugiperda (fall armyworm) EcRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetProtein ultraspiracle(Fruit fly)
Csiro Materials Science and Engineering and Csiro Food and Nutritional Sciences

Curated by ChEMBL
LigandPNGBDBM50226672(makisterone A | CHEMBL255034)
Affinity DataIC50: 1.38E+3nMAssay Description:Binding affinity to Drosophila melanogaster EcRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed