BDBM50226527 CHEMBL107251::N-(3-(AMINOMETHYL)BENZYL)ACETAMIDINE::N-(3-(aminomethyl)benzyl)acetimidamide::N-(3-Aminomethyl-benzyl)-acetamidine::N-(3-aminomethyl)benzylacetimidamide::N-[3-(aminomethyl)benzyl]ethanimidamide::N-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide::[N-(3-aminomethyl)benzylactamidine]
SMILES CC(N)=NCc1cccc(CN)c1
InChI Key InChIKey=RODUKNYOEVZQPR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 23 hits for monomerid = 50226527
TargetNitric oxide synthase, endothelial(Bovine)
University of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
University of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of bovine recombinant eNOS using [3H]L-arginine substrate assessed as formation of [3H]L-citruline by liquid scintillation counting analys...More data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:Inhibition of recombinant human iNOS assessed as reduction of L-[14C]arginine to L-[14C]citrulline conversion in presence of NADPHMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bovine)
University of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
University of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length N-terminal his-tagged bovine eNOS (2 to 1205 residues) expressed in Escherichia coli preincubated for 15 mins followed by N...More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of N-terminal his6-tagged recombinant human iNOS expressed in Escherichia coli preincubated for 15 mins followed by NADPH addition and mea...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of iNOS (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.12E+4nMAssay Description:Inhibition of human eNOS assessed as reduction in L-[3H]-citrulline level using L-[3H]-arginine as substrate incubated for 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of human nNOS assessed as reduction in L-[3H]-citrulline level using L-[3H]-arginine as substrate incubated for 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Inhibition of human iNOS assessed as reduction in L-[3H]-citrulline level using L-[3H]-arginine as substrate incubated for 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 3.04E+5nMAssay Description:Inhibition of human eNOS using L-argininge as substrate preincubated for 15 mins followed by NADPH addition and measured after 20 mins by OPA/NAC rea...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of recombinant human nNOS expressed in Escherichia coli using L-arginine as substrate preincubated for 15 mins followed by NADPH addition ...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant N-terminal His-tagged human iNOS expressed in Escherichia coli using L-arginine as substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of recombinant rat nNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in pr...More data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bovine)
University of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
University of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
Affinity DataIC50: 3.84E+5nMAssay Description:Inhibition of recombinant bovine eNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bovine)
University of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
University of Chieti&Quot;G. D'Annunzio&Quot
Curated by ChEMBL
Affinity DataIC50: 1.10E+6nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+6nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse recombinant iNOS using [3H]L-arginine substrate assessed as formation of [3H]L-citruline by liquid scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Inhibition of recombinant human nNOS assessed as reduction of L-[14C]arginine to L-[14C]citrulline conversion in presence of NADPHMore data for this Ligand-Target Pair
Affinity DataKi: 7.30E+3nMAssay Description:Binding affinity nNOSMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+4nMAssay Description:Inhibition of recombinant human eNOS assessed as reduction of L-[14C]arginine to L-[14C]citrulline conversion in presence of NADPHMore data for this Ligand-Target Pair