BDBM50226223 CHEMBL302219

SMILES Cc1nc(O)c(N)cc1-c1ccncc1

InChI Key InChIKey=PODUQVUYRAXKPI-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50226223   

LigandPNGBDBM50226223(CHEMBL302219)
Affinity DataIC50: 3.10E+4nMAssay Description:Cardiotonic effect by inhibition of cAMP phosphodiesterase (PDE III)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2018
Entry Details Article
PubMed
TargetAurora kinase B/Inner centromere protein(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50226223(CHEMBL302219)
Affinity DataKi:  2.57E+4nMAssay Description:Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50226223(CHEMBL302219)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50226223(CHEMBL302219)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of full length N-terminal His-tagged Aurora A (unknown origin) using fluorescence-labeled FL-Peptide 21 as substrate after 60 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed