BDBM50225827 (E)-3-(7-(2-(2,4-difluorophenyl)ethynyl)-4-oxo-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl)benzonitrile::CHEMBL393385

SMILES Fc1ccc(C#Cc2ccc3N=C(CC(=O)Nc3c2)c2cccc(c2)C#N)c(F)c1

InChI Key InChIKey=LZRDCWOBOTZABS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50225827   

TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50225827((E)-3-(7-(2-(2,4-difluorophenyl)ethynyl)-4-oxo-4,5...)
Affinity DataIC50: 480nMAssay Description:Displacement of [3H]LY354740 from rat mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed