BDBM50225356 (2E)-N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}-3-phenylacrylamide::CHEMBL408486::N-(1-((6-fluoronaphthalen-2-yl)methyl)piperidin-4-yl)cinnamamide

SMILES Fc1ccc2cc(CN3CCC(CC3)NC(=O)\C=C\c3ccccc3)ccc2c1

InChI Key InChIKey=CBQSNFCXAYXVQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50225356   

TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50225356((2E)-N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4...)
Affinity DataIC50: 9.70E+3nMAssay Description:Antagonist activity at human CCR3 expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50225356((2E)-N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4...)
Affinity DataIC50: 9.70E+3nMAssay Description:Antagonist activity at CCR3 expressed in B300-19 cells assessed as inhibition of eotaxin-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed