BDBM50224844 1-[6-(4-fluoro-phenoxy)-pyridin-3-yl]-1,7,9-triaza-spiro[4.5]decane-6,8,10-trione::CHEMBL398966

SMILES Fc1ccc(Oc2ccc(cn2)N2CCCC22C(=O)NC(=O)NC2=O)cc1

InChI Key InChIKey=AOSUTMRBALZLRS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224844   

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50224844(1-[6-(4-fluoro-phenoxy)-pyridin-3-yl]-1,7,9-triaza...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50224844(1-[6-(4-fluoro-phenoxy)-pyridin-3-yl]-1,7,9-triaza...)
Affinity DataIC50: 1.57nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed