BDBM50224763 2-chloro-N6-(R)-3-tetrahydrofuranyl-9H-(2-C-methyl-5-N-methylthiocarbamoyl-beta-D-ribofuranosyl)adenine::CHEMBL254896

SMILES CNC(=S)OC[C@H]1O[C@@H](n2cnc3c(N[C@@H]4CCOC4)nc(Cl)nc23)[C@](C)(O)[C@@H]1O

InChI Key InChIKey=RYGIFFCNIBVJRY-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50224763   

TargetAdenosine receptor A1(Guinea pig)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50224763(2-chloro-N6-(R)-3-tetrahydrofuranyl-9H-(2-C-methyl...)
Affinity DataKi:  276nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in pig cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50224763(2-chloro-N6-(R)-3-tetrahydrofuranyl-9H-(2-C-methyl...)
Affinity DataKi:  615nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in bovine cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50224763(2-chloro-N6-(R)-3-tetrahydrofuranyl-9H-(2-C-methyl...)
Affinity DataKi:  837nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50224763(2-chloro-N6-(R)-3-tetrahydrofuranyl-9H-(2-C-methyl...)
Affinity DataKi:  1.21E+4nMAssay Description:Agonist activity at human recombinant adenosine A2B receptor expressed in CHO cells assessed as activation of adenylyl cyclase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50224763(2-chloro-N6-(R)-3-tetrahydrofuranyl-9H-(2-C-methyl...)
Affinity DataKi:  1.59E+4nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50224763(2-chloro-N6-(R)-3-tetrahydrofuranyl-9H-(2-C-methyl...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed