BDBM50224387 1-(2-chloro-2-phenylethyl)-N-(2-chlorobenzyl)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL236375::N-(2-chlorobenzyl)-1-(2-chloro-2-phenylethyl)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

SMILES CSc1nc(NCc2ccccc2Cl)c2cnn(CC(Cl)c3ccccc3)c2n1

InChI Key InChIKey=XNWHPCMDUYIUSL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50224387   

TargetTyrosine-protein kinase ABL1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50224387(1-(2-chloro-2-phenylethyl)-N-(2-chlorobenzyl)-6-(m...)
Affinity DataKi:  89nMAssay Description:Inhibition human recombinant Abl using Abtide peptide substrate in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50224387(1-(2-chloro-2-phenylethyl)-N-(2-chlorobenzyl)-6-(m...)
Affinity DataKi:  90nMAssay Description:Inhibition of human recombinant AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50224387(1-(2-chloro-2-phenylethyl)-N-(2-chlorobenzyl)-6-(m...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50224387(1-(2-chloro-2-phenylethyl)-N-(2-chlorobenzyl)-6-(m...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed