BDBM50224382 CHEMBL399627::N-(3-bromophenyl)-1-(2-chloro-2-(4-fluorophenyl)ethyl)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

SMILES CSc1nc(Nc2cccc(Br)c2)c2cnn(CC(Cl)c3ccc(F)cc3)c2n1

InChI Key InChIKey=VHLDCFYRQZGLBG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50224382   

TargetTyrosine-protein kinase ABL1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50224382(N-(3-bromophenyl)-1-(2-chloro-2-(4-fluorophenyl)et...)
Affinity DataKi:  150nMAssay Description:Inhibition of human recombinant AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50224382(N-(3-bromophenyl)-1-(2-chloro-2-(4-fluorophenyl)et...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50224382(N-(3-bromophenyl)-1-(2-chloro-2-(4-fluorophenyl)et...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed