BDBM50224217 2-(2,5-difluorophenylamino)-5-isopropylthiazol-4(5H)-one::CHEMBL236174

SMILES CC(C)c1sc(Nc2cc(F)ccc2F)nc1O

InChI Key InChIKey=XZKMZCXJUBITPX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224217   

LigandPNGBDBM50224217(2-(2,5-difluorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human 11-beta-HSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50224217(2-(2,5-difluorophenylamino)-5-isopropylthiazol-4(5...)
Affinity DataKi:  12nMAssay Description:Inhibition of human 11-beta-HSD1 by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed