BDBM50224213 2-(o-toluidino)-5-isopropylthiazol-4(5H)-one::CHEMBL238095

SMILES CC(C)c1sc(Nc2ccccc2C)nc1O

InChI Key InChIKey=CSOPFNOFIZHDML-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50224213   

LigandPNGBDBM50224213(2-(o-toluidino)-5-isopropylthiazol-4(5H)-one | CHE...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human 11-beta-HSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50224213(2-(o-toluidino)-5-isopropylthiazol-4(5H)-one | CHE...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human 11-beta-HSD1 in presence of 3% HSA by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50224213(2-(o-toluidino)-5-isopropylthiazol-4(5H)-one | CHE...)
Affinity DataKi:  27nMAssay Description:Inhibition of human 11-beta-HSD1 by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed