BDBM50224212 5-isopropyl-2-(2-(trifluoromethyl)phenylamino)thiazol-4(5H)-one::CHEMBL396618

SMILES CC(C)c1sc(Nc2ccccc2C(F)(F)F)nc1O

InChI Key InChIKey=QXZHZIYXCGQXGZ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50224212   

LigandPNGBDBM50224212(5-isopropyl-2-(2-(trifluoromethyl)phenylamino)thia...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human 11-beta-HSD1 in presence of 3% HSA by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50224212(5-isopropyl-2-(2-(trifluoromethyl)phenylamino)thia...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human 11-beta-HSD1 in CHO cells assessed as conversion of cortisone to cortisolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50224212(5-isopropyl-2-(2-(trifluoromethyl)phenylamino)thia...)
Affinity DataKi:  23nMAssay Description:Inhibition of human 11-beta-HSD1 by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed