BDBM50224152 4-hydroxy-piperidine-1-carboxylic acid 4-(5-trifluoromethylpyridin-2-yloxy)-phenyl ester::CHEMBL238994

SMILES OC1CCN(CC1)C(=O)Oc1ccc(Oc2ccc(cn2)C(F)(F)F)cc1

InChI Key InChIKey=CKHKKOJRCBFWTB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50224152   

TargetHormone-sensitive lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224152(4-hydroxy-piperidine-1-carboxylic acid 4-(5-triflu...)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human hormone-sensitive lipaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224152(4-hydroxy-piperidine-1-carboxylic acid 4-(5-triflu...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of butyrylcholine esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224152(4-hydroxy-piperidine-1-carboxylic acid 4-(5-triflu...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of acetylcholine esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50224152(4-hydroxy-piperidine-1-carboxylic acid 4-(5-triflu...)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human HSL expressed in Sf9 insect cells using PNPB as substrate measured after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed