BDBM50224126 CHEMBL398383::Ehyl-2-methyl-1-[4-(methylsulfonyl)phenyl]-5-[3,4-(difluoro)phenyl]-1H-pyrrol-3-acetate

SMILES CCOC(=O)Cc1cc(-c2ccc(F)c(F)c2)n(c1C)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=BEWBVGPOPQDTAO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224126   

TargetProstaglandin G/H synthase 2(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50224126(Ehyl-2-methyl-1-[4-(methylsulfonyl)phenyl]-5-[3,4-...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of COX2 in LPS-stimulated J774 cells assessed as inhibition of PGE2 levels by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50224126(Ehyl-2-methyl-1-[4-(methylsulfonyl)phenyl]-5-[3,4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1 in mouse J774 cells assessed as arachidonic acid-induced PGE2 levels by radio immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed