BDBM50224029 6-(4-(2-((S)-3-(3-benzyl-2-oxoindolin-4-yloxy)-2-hydroxypropylamino)-2-methylpropyl)phenoxy)nicotinamide::CHEMBL401335

SMILES CC(C)(Cc1ccc(Oc2ccc(cn2)C(N)=O)cc1)NC[C@H](O)COc1cccc2NC(=O)C(Cc3ccccc3)c12

InChI Key InChIKey=NNYKUVQEGQHDMX-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50224029   

TargetBeta-2 adrenergic receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50224029(6-(4-(2-((S)-3-(3-benzyl-2-oxoindolin-4-yloxy)-2-h...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human beta-2 adrenergic receptor expressed in CHO cells assessed as cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50224029(6-(4-(2-((S)-3-(3-benzyl-2-oxoindolin-4-yloxy)-2-h...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50224029(6-(4-(2-((S)-3-(3-benzyl-2-oxoindolin-4-yloxy)-2-h...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed