BDBM50223936 6-((5,5-dimethyl-2,4-dioxooxazolidin-3-yl)methyl)-7-neopentyl-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile::CHEMBL249759

SMILES CC(C)(C)Cn1c(CN2C(=O)OC(C)(C)C2=O)cc2cnc(nc12)C#N

InChI Key InChIKey=RHNDYLRFGDUEEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223936   

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223936(6-((5,5-dimethyl-2,4-dioxooxazolidin-3-yl)methyl)-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223936(6-((5,5-dimethyl-2,4-dioxooxazolidin-3-yl)methyl)-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed