BDBM50223935 CHEMBL399842::N-(4-((2-cyano-7-neopentyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methyl)phenyl)-2,2,2-trifluoroethanesulfonamide

SMILES CC(C)(C)Cn1c(Cc2ccc(NS(=O)(=O)CC(F)(F)F)cc2)cc2cnc(nc12)C#N

InChI Key InChIKey=SSEVORDVTHEORU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223935   

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223935(N-(4-((2-cyano-7-neopentyl-7H-pyrrolo[2,3-d]pyrimi...)
Affinity DataIC50: 440nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223935(N-(4-((2-cyano-7-neopentyl-7H-pyrrolo[2,3-d]pyrimi...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed