BDBM50223913 6-((1,3-dioxo-2,8-diazaspiro[4.5]decan-2-yl)methyl)-7-neopentyl-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile::7-(2,2-Dimethyl-propyl)-6-(1,3-dioxo-2,8-diaza-spiro[4.5]dec-2-ylmethyl)-7H-pyrrolo[2,3-d] pyrimidine-2-carbonitrile::7-(2,2-dimethyl-propyl)-6-(1,3-dioxo-2,8-diaza-spiro[4.5]dec-2-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile::CHEMBL249966

SMILES CC(C)(C)Cn1c(CN2C(=O)CC3(CCNCC3)C2=O)cc2cnc(nc12)C#N

InChI Key InChIKey=GXGLUMCONRSMLM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223913   

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223913(7-(2,2-dimethyl-propyl)-6-(1,3-dioxo-2,8-diaza-spi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rat)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50223913(7-(2,2-dimethyl-propyl)-6-(1,3-dioxo-2,8-diaza-spi...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat recombinant cathepsin K expressed in Sf21 cells by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed