BDBM50223757 CHEMBL291976

SMILES [H][C@@](O)(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@]1([H])c2ccccc2C[C@@]1([H])O)c1ccccc1

InChI Key InChIKey=SWOZAFWHDLVMNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223757   

LigandPNGBDBM50223757(CHEMBL291976)
Affinity DataIC50: 71nMAssay Description:Inhibition of human gamma-secretase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2018
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50223757(CHEMBL291976)
Affinity DataIC50: 71nMAssay Description:Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2018
Entry Details Article
PubMed