BDBM50223647 CHEMBL112366

SMILES Nc1cc2CCN3c2c(c1)C(=N[C@@H](NC(=O)c1ccncc1)C3=O)c1ccccc1

InChI Key InChIKey=KUPGNWKDDKVLPV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50223647   

LigandPNGBDBM50223647(CHEMBL112366)
Affinity DataIC50: 270nMAssay Description:Inhibition of phosphodiesterase 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50223647(CHEMBL112366)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1/5 isozyme (PDE1/5) mixture isolated from the guinea pig trachea.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50223647(CHEMBL112366)
Affinity DataIC50: 500nMAssay Description:Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50223647(CHEMBL112366)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of phosphodiesterase 3 (PDE3) isolated from the dog aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50223647(CHEMBL112366)
Affinity DataIC50: 654nMAssay Description:Inhibition of [3H]rolipram binding to Wistar rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed