BDBM50223597 CHEMBL95777

SMILES Clc1cccc(c1)-n1nc(cc1\C=C\c1c[nH]c2ccc(Cl)cc12)C1CCNCC1

InChI Key InChIKey=PWSCBDGDOLMHFP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50223597   

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223597(CHEMBL95777)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2018
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223597(CHEMBL95777)
Affinity DataIC50: 9.14E+5nMAssay Description:Human DNA topoisomerase II relaxation activity was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2018
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223597(CHEMBL95777)
Affinity DataIC50: 3.20E+4nMAssay Description:Iinhibitory activity against Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Escherichia coli (strain K12))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223597(CHEMBL95777)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against decatenation of DNA topoisomerase IV isolated from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223597(CHEMBL95777)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibitory activity against supercoiling activity of DNA gyrase isolated from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50223597(CHEMBL95777)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of Escherichia coli DNA gyrase using positively supercoiled pBR322 DNA as substrate incubated for 1 hr by based agarose gel electrophoresi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50223597(CHEMBL95777)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed