BDBM50223567 3-bromo-5-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL401303::US8580782, 8

SMILES Clc1ccccc1-c1cc(NCc2cccnc2)n2ncc(Br)c2n1

InChI Key InChIKey=KVSIJRIBZQPYQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223567   

TargetCyclin-dependent kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50223567(US8580782, 8 | CHEMBL401303 | 3-bromo-5-(2-chlorop...)
Affinity DataIC50: 3nMpH: 8.0Assay Description:CDK2 kinase assays (either cyclin A or cyclin E-dependent) were performed in low protein binding 96-well plates (Corning Inc., Corning, N.Y.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details
Go to US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50223567(US8580782, 8 | CHEMBL401303 | 3-bromo-5-(2-chlorop...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed