BDBM50223566 CHEMBL429453::N-ethyl-N-((1s,4s)-4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)-3,4-dimethoxybenzenesulfonamide

SMILES CCN([C@H]1CC[C@H](CC1)N1CCN(CC1)c1ccccc1OC(C)C)S(=O)(=O)c1ccc(OC)c(OC)c1

InChI Key InChIKey=LVRHAAKFXRNPFH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50223566   

TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223566(N-ethyl-N-((1s,4s)-4-(4-(2-isopropoxyphenyl)pipera...)
Affinity DataKi:  15nMAssay Description:Binding affinity to human cloned adrenergic Alpha-1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223566(N-ethyl-N-((1s,4s)-4-(4-(2-isopropoxyphenyl)pipera...)
Affinity DataKi:  22nMAssay Description:Binding affinity to human cloned adrenergic alpha-1d receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223566(N-ethyl-N-((1s,4s)-4-(4-(2-isopropoxyphenyl)pipera...)
Affinity DataKi:  113nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50223566(N-ethyl-N-((1s,4s)-4-(4-(2-isopropoxyphenyl)pipera...)
Affinity DataKi:  326nMAssay Description:Binding affinity to human cloned adrenergic alpha-1b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed