BDBM50223487 9-fluoro-2-phenyl-3,6-dihydro-1,3,6-triaza-cyclopenta[l]phenanthren-7-one::CHEMBL436640

SMILES Fc1ccc2c3[nH]c(nc3c3cc[nH]c(=O)c3c2c1)-c1ccccc1

InChI Key InChIKey=RKEVLNISIKYNSD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223487   

TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223487(9-fluoro-2-phenyl-3,6-dihydro-1,3,6-triaza-cyclope...)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human Chk1 expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50223487(9-fluoro-2-phenyl-3,6-dihydro-1,3,6-triaza-cyclope...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mPGES-1 in IL-1beta-stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 formation incubated for 15 mins using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed