BDBM50223461 6-(3-aminopropyl)-9-(1H-pyrazol-4-yl)benzo[h]isoquinolin-1(2H)-one::CHEMBL249224

SMILES NCCCc1cc2cc[nH]c(=O)c2c2cc(ccc12)-c1cn[nH]c1

InChI Key InChIKey=NCDJUOZXHZEKAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223461   

TargetSerine/threonine-protein kinase Chk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50223461(6-(3-aminopropyl)-9-(1H-pyrazol-4-yl)benzo[h]isoqu...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human Chk1 expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed