BDBM50223308 CHEMBL398481::N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitrobenzenamine::US11459308, Compound PPZ-1

SMILES CN1CCN(CC1)c1ccc(c(NC(c2ccccc2)c2ccccc2)c1)[N+]([O-])=O

InChI Key InChIKey=RHCKSABVOKGXBN-UHFFFAOYSA-N

Data  1 KI  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50223308   

TargetEnvelope glycoprotein(REBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 1.20E+3nMAssay Description:Recombinant vesicular stomatitis viruses (VSVs) (serotype Indiana) expressing eGFP and EBOV, SUDV, or BDBV GP in place of VSV G, as well as those exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(ZEBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 2.30E+3nMAssay Description:The authentic filoviruses Ebola virus/H. sapiens-tc/COD/1995/Kikwit-9510621 (EBOV/Kik-9510621; EBOV-Zaire 1995 ) (Jahrling et al., J. Infect. Dis., 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(REBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 1.20E+3nMAssay Description:Recombinant vesicular stomatitis viruses (VSVs) (serotype Indiana) expressing eGFP and EBOV, SUDV, or BDBV GP in place of VSV G, as well as those exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(ZEBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 2.30E+3nMAssay Description:The authentic filoviruses Ebola virus/H. sapiens-tc/COD/1995/Kikwit-9510621 (EBOV/Kik-9510621; EBOV-Zaire 1995 ) (Jahrling et al., J. Infect. Dis., 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(REBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 1.20E+3nMAssay Description:Recombinant vesicular stomatitis viruses (VSVs) (serotype Indiana) expressing eGFP and EBOV, SUDV, or BDBV GP in place of VSV G, as well as those exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(ZEBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 2.30E+3nMAssay Description:The authentic filoviruses Ebola virus/H. sapiens-tc/COD/1995/Kikwit-9510621 (EBOV/Kik-9510621; EBOV-Zaire 1995 ) (Jahrling et al., J. Infect. Dis., 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(REBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 1.20E+3nMAssay Description:Recombinant vesicular stomatitis viruses (VSVs) (serotype Indiana) expressing eGFP and EBOV, SUDV, or BDBV GP in place of VSV G, as well as those exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(ZEBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 2.30E+3nMAssay Description:The authentic filoviruses Ebola virus/H. sapiens-tc/COD/1995/Kikwit-9510621 (EBOV/Kik-9510621; EBOV-Zaire 1995 ) (Jahrling et al., J. Infect. Dis., 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(REBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 1.20E+3nMAssay Description:Recombinant vesicular stomatitis viruses (VSVs) (serotype Indiana) expressing eGFP and EBOV, SUDV, or BDBV GP in place of VSV G, as well as those exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(ZEBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 2.30E+3nMAssay Description:The authentic filoviruses Ebola virus/H. sapiens-tc/COD/1995/Kikwit-9510621 (EBOV/Kik-9510621; EBOV-Zaire 1995 ) (Jahrling et al., J. Infect. Dis., 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(ZEBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 2.30E+3nMAssay Description:The authentic filoviruses Ebola virus/H. sapiens-tc/COD/1995/Kikwit-9510621 (EBOV/Kik-9510621; EBOV-Zaire 1995 ) (Jahrling et al., J. Infect. Dis., 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(REBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 1.20E+3nMAssay Description:Recombinant vesicular stomatitis viruses (VSVs) (serotype Indiana) expressing eGFP and EBOV, SUDV, or BDBV GP in place of VSV G, as well as those exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(ZEBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 2.30E+3nMAssay Description:The authentic filoviruses Ebola virus/H. sapiens-tc/COD/1995/Kikwit-9510621 (EBOV/Kik-9510621; EBOV-Zaire 1995 ) (Jahrling et al., J. Infect. Dis., 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(REBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 1.20E+3nMAssay Description:Recombinant vesicular stomatitis viruses (VSVs) (serotype Indiana) expressing eGFP and EBOV, SUDV, or BDBV GP in place of VSV G, as well as those exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(ZEBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 2.30E+3nMAssay Description:The authentic filoviruses Ebola virus/H. sapiens-tc/COD/1995/Kikwit-9510621 (EBOV/Kik-9510621; EBOV-Zaire 1995 ) (Jahrling et al., J. Infect. Dis., 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(REBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 1.20E+3nMAssay Description:Recombinant vesicular stomatitis viruses (VSVs) (serotype Indiana) expressing eGFP and EBOV, SUDV, or BDBV GP in place of VSV G, as well as those exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(REBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 1.20E+3nMAssay Description:Recombinant vesicular stomatitis viruses (VSVs) (serotype Indiana) expressing eGFP and EBOV, SUDV, or BDBV GP in place of VSV G, as well as those exp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetEnvelope glycoprotein(ZEBOV)
Microbiotix

US Patent
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataIC50: 2.30E+3nMAssay Description:The authentic filoviruses Ebola virus/H. sapiens-tc/COD/1995/Kikwit-9510621 (EBOV/Kik-9510621; EBOV-Zaire 1995 ) (Jahrling et al., J. Infect. Dis., 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 6(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50223308(N-benzhydryl-5-(4-methylpiperazin-1-yl)-2-nitroben...)
Affinity DataKi:  4.49E+3nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed