BDBM50222834 CHEMBL398713::N-(5-tert-butyl-3-(cyclopropylmethyl)-4-methylthiazol-2(3H)-ylidene)-2-methoxy-5-(trifluoromethyl)benzamide

SMILES COc1ccc(cc1C(=O)\N=c1/sc(c(C)n1CC1CC1)C(C)(C)C)C(F)(F)F

InChI Key InChIKey=UBYJCLVXLMEREE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222834   

TargetCannabinoid receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50222834(N-(5-tert-butyl-3-(cyclopropylmethyl)-4-methylthia...)
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [3H]CP-55940 form human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50222834(N-(5-tert-butyl-3-(cyclopropylmethyl)-4-methylthia...)
Affinity DataEC50:  0.620nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50222834(N-(5-tert-butyl-3-(cyclopropylmethyl)-4-methylthia...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed