BDBM50222825 2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-pyridin-4-yl-ethyl)-isonicotinamide::CHEMBL249023

SMILES O=C(COc1ccc(cc1)C12CC3CC(CC(C3)C1)C2)Nc1cc(ccn1)C(=O)NCCc1ccncc1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222825   

TargetHypoxia-inducible factor 1-alpha(Human)
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222825(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of hypoxia induced HIF1-alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222825(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of hypoxia induced HIF1-alpha transcriptional activity in human Sk-Hep1 cells by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50222825(2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of hypoxia induced HIF1-alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed